Cant say I do. If anything its made my relationships stronger.
In any case id say fuk the relationships with everyone then, and try to figure out what drives you in life. Think career wise and hobby wise and just own the sh1t out of them. For me...i have one semester left of school to become a personal trainer and my hobbies include poker, golf, sports, country music. These things absolutely make me happy and you need to find things that do this for you. Sure, golf and sports can be frustrating when you lose....but the competition i feel is necessary for men.
So here is an example of a recent Saturday:
-Wakeup
-Study my ACSM materials(Personal Trainer Certification Test)
-Study/Play Poker
-Go to the gym
-Go tailgate for a country concert(finds HB to hook up with and slams it)
-Bed
So you see im doing stuff all day that i thoroughly enjoy. Game doesnt even really come into play until late in the day when i start drinking, but even then its presence is minimal because i have internalized knowledge ive learned, so its just second nature now. I dont go to the concert "looking to hookup", but im a social guy and when everyone drinks....everyone is friendly. One thing leads to another and bam.
So you see the emphasis is on MY LIFE and MY INTERESTS. Not game and not women. Find those things and start enjoying life again.