Good question. Never done it, but I would want to given the chance. I imagine it would be nothing special physically, more of a mental thing like speakeasy says. Though, I am already past the age when most attractive girls not waiting for marriage have lost it, so if it never happens, no big deal. I think it's the sort of thing that you experience if you start having sex early when girls your age are still virgins. Otherwise you need to either be into much younger girls (I'm not) or by chance find one of the few older attractive women that still are for whatever reason.
On the other hand, a few months ago my girlfriend had this weird muscle cramp in her ***** that made it extremely tight to the point where it was literally difficult to get it in even with tons of wetness and lube, and it was painful for her to the point we had to stop. Seemed to resolve itself a few hours later. Its never happened to me before or since, but based on that one experience, I don't know if I would even have the patience for a virgin, and I don't like causing pain beyond the rough sex threshold. That was the most virgin like sex I've had and there was nothing appealing about it, just frustrating.