I think you need to take some time away from the world of picking up women, and work on yourself. You have a very bad self-image. I bet every time a woman turns you down or is non-responsive, you feel terrible. It's a sad state of affairs.
Your ego is attacked when you have your self-image deflated by a woman, so you need to rework your self-image and not let woman be a deity. You should not let your desires for success with women be a part of your self-image and know that it's just fun for you. Then guess what! You won't feel deflated, and you'll become normal with women just as you are with everyone else. Get their reactions toward you out of your self-image, and you'll stop acting awkward around them.
Dude, I get turned down, flaked on, and stood up, but that's not my story. It doesn't affect me because it's not my main priority in life. It's not what's so important to me, and because of that, I have success, too. I have many successes with women because I've decided to tear down that false pedestal that I once had built up out of my reach. If a woman isn't into me, I just look at as if she has bad taste, and to me IT'S SO TRUE. There is no reason for a woman not to want me. NONE! If she doesn't, she's only doing me a favor to go find women who do enjoy me.
Women's reaction to you is not that important if you know who you are. Just talk to them without worrying about an outcome. Have fun. That's all they want is to have fun. Fun with you or without you. If they feel that you're going to be all over them, they won't be interested.
And remember, everyone gets turned down at one time or another. It's not something you should worry about. That means you are part of one of the largest clubs in the entire world. It just is...